Current problem with the pressure in the hangar. When I close the hangar while the cargo arm is in motion it doesn't register as being "inside" so the external pressure doesn't equalize. While normally it takes a minute or two to equalize and the airlock door to automatically open, it still registers as being outside and all the lights to the base remain off. I can solve it by exiting and re-entering the base from an alternate exit, but it seems like an issue that needs to be addressed.
Second, perhaps you should consider reversing the oxygen input on the large dome to an oxygen output. Once your base is filled with oxygen, any excess can be moved into a spare tank which can be used for other projects and free up wells for more water.
Also, too many meteorites. I don't need that much uranium in the game and having it constantly fall out of the sky makes searching caves unnecessary.
Consider having the mining container ramp store the container trailer. That way I can leave the cargo container there to completely fill up on the mined ore, increasing the storage capacity of the miner from 1000 units to "until the cargo container is full".
And what about fish farms? A vegetarian diet isn't good. Maybe start off with aquariums and then eventually a large dome but with a crap ton of water where you can raise and farm fish for food.
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